A New Base-Modified Deoxycytidine Capable of Base Pairing With Guanine Using Four Hydrogen Bonds

Content Synthetic scheme of phosphoramidite 9b ------------------------------------------------------------------S3 Figure S1 ------------------------------------------------------------------------------------------------------S4 Figure S2 ------------------------------------------------------------------------------------------------------S4 Figure S3 ------------------------------------------------------------------------------------------------------S5 Synthesis of DNA oligonucleotides containing dCPyc (ODNs1-4) ----------------------------------S6 Table S1 ------------------------------------------------------------------------------------------------------S6 Synthesis of DNA oligonucleotides containing dCInc (ODN5 and ODN6) -----------------------S7 Table S2 -------------------------------------------------------------------------------------------------------S7 Figure S4 -----------------------------------------------------------------------------------------------------S7 Synthesis of Dickerson Drew sequenced-ODN7 incorporating dCPyc -----------------------------S8 Figure S5 -----------------------------------------------------------------------------------------------------S8 1H-NMR of 1 ----------------------------------------------------------------------------------------------S9 13C-NMR of 1 -------------------------------------------------------------------------------------------------S10 1H-NMR of 2 ----------------------------------------------------------------------------------------------S11 13C-NMR of 2 -------------------------------------------------------------------------------------------------S12 1H-NMR of 5a ------------------------------------------------------------------------------------------------S13 13C-NMR of 5a ------------------------------------------------------------------------------------------------S14 1H-NMR of 5b ------------------------------------------------------------------------------------------------S15 13C-NMR of 5b ------------------------------------------------------------------------------------------------S16 1H-NMR of 5c -----------------------------------------------------------------------------------------------S17 13C-NMR of 5c ------------------------------------------------------------------------------------------------S18 1H-NMR of 6a -----------------------------------------------------------------------------------------------S19 13C-NMR of 6a ------------------------------------------------------------------------------------------------S20 1H-NMR of 6b -----------------------------------------------------------------------------------------------S21